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3.
J Indian Med Assoc ; 2001 Dec; 99(12): 704-9
Article in English | IMSEAR | ID: sea-95990

ABSTRACT

Trigeminal neuralgia is the most frequent cranial neuralgia, the incidence being 1 per 1,000,00 persons per year. It presents with stabbing pain often in the distribution of the mandibular and maxillary divisions of the trigeminal nerve. An accurate history of pain is important in the diagnosis of trigeminal neuralgia. A patient with tic douloureux and no neurological abnormality on clinical examination does not need diagnostic tests. The available options for management of trigeminal neuralgia are: Pharmacotherapy, destructive procedures and non-destructive procedures. The pharmacotherapy includes (i) monotherapy with one anticonvulsant, (ii) combined therapy with more than one anticonvulsant, (iii) add-on therapy with newer drugs and (iv) polytherapy with anticonvulsant + add-on drugs + antidepressants/anxiolytics. Destructive procedures include (i) non-surgical methods--injections along trigeminal pathways, percutaneous trigeminal radiofrequency thermocoagulation and (ii) surgical methods--trigeminal branch avulsion or peripheral neurectomy, avulsion of trigeminal nerve, trigeminal tractotomy, radiosurgery. Though various modalities of treatment are available for the management of trigeminal neuralgia, pharmacotherapy with carbamazepine still remains the first line of treatment. The alternative approach followed at most centres is percuatenous Gasserian rhizolysis (chemical/radiofrequency thermal) or microvascular decompression.


Subject(s)
Analgesics, Non-Narcotic/therapeutic use , Baclofen/therapeutic use , Carbamazepine/therapeutic use , Humans , Phenytoin/therapeutic use , Pimozide/therapeutic use , Radiosurgery , Trigeminal Ganglion/physiopathology , Trigeminal Neuralgia/diagnosis
4.
An. otorrinolaringol. mex ; 40(4): 174-6, sept.-nov. 1995.
Article in Spanish | LILACS | ID: lil-174010

ABSTRACT

Para investigar sobre la participación del nervio trigémino y del músculo tensor del tímpano en el reflejo acústico humano se planteó un estudio prospectivo en once pacientes portadores de neuralgia del trigémino y programados para microcompresión del Ganglio de Gasser con balón percutáneo. Todos los pacientes presentaron estudios audiológico normales, incluyendo umbrales tonales, BéKésy, logoaudiometría, potenciales evocados y timpanograma, así como integridad del nervio facial detectada por clínica y por electroneuronografía. Los once pacientes presentaban ausencia del reflejo acústico. Seis meses después de la compresión del Ganglio de Gasser, tres pacientes presentaron reflejo acústico normal y en el resto permaneció ausente. Los ocho pacientes que no presentaron reflejo cursaron con paresia de músculos masticadores. Nuestros resultados parecen indicar que para la integridad del reflejo acústico es necesario tanto el sistema facial como el trigeminal. El reflejo acústico puede ser una prueba útil en el estudio de la neuralgia de trigémino


Subject(s)
Humans , Male , Female , Audiology , Evoked Potentials, Auditory, Brain Stem/physiology , Trigeminal Ganglion/physiopathology , Trigeminal Nerve/physiology , Trigeminal Neuralgia/diagnosis , Ear, Middle/anatomy & histology , Reflex, Acoustic/physiology , Tensor Tympani/physiology , Acoustic Impedance Tests
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